Regeneron Pharmaceuticals Intern - Process Sciences in Rensselaer, New York
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious disease.
Project Description: The proposed project will investigate potential clearance of endotoxin on downstream purification steps. The effects of various steps with their associated resins and buffer matrices will be analyzed based on the clearance of endotoxin. The use of Design of Experiment (DoE) and other statistical analysis will be performed throughout the study.
Business benefit/advantage for IOPS: The information that will be gathered from this proposed project will address gaps in the understanding of downstream purification steps with regards to the clearance of endotoxin. In manufacturing endotoxin has been introduced into several steps in the downstream unit operation, it is important that the endotoxin is cleared from all subsequent components. This proposed study will determine which downstream unit operations are sensitive to endotoxin clearance. The information from this study will be useful for providing further understanding of endotoxin effects on downstream operations and can be helpful during studies into process investigations.
This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron’s unwavering commitment to combining good science & good business.
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